- "MTM 1: An explainable AI system for microbiome-based host phenotype prediction", NSF 2025451, 10/01/2020-09/30/2023
- "Subtractive assembly approaches for inferring disease-associated microbial genes and pathways from microbiome sequencing data”, NIH, 1R01AI143254, 11/5/2018-10/31/2022 (PI)
- "Graph-centric approaches to metatranscriptomic and metaproteomic data analysis", NIH 1R01AI108888, 8/1/2014-7/31/2019
- "Identification and evolutionary study of mobile genetic elements", NSF DBI-1262588, 9/1/2013-8/31/2017 (co-PI)
- "Lung Microbiome and Pulmonary Inflammation/Immunity in HIV Infection”, NIH NHLBI UO1HL098960, 10/1/09–9/30/14 (Co-investigator; PI: Twigg, IUPUI)
- "CAREER: Computational Protein Function Annotation for Metagenomics", NSF DBI-0845685, 9/15/2009-8/31/2014
- "Fragment Assembly and Metabolic/Species Diversity Analysis for the Human Microbiome" NIH 1R01HG004908-01, 09/26/2008-07/31/2012. See the news release at NIH; see related news at GenomeWeb
- "Flexible Protein Structure Alignment Program and Server", NSF DBI-0349600, 09/01/2004–08/31/2007 (Co-PI; PI: Adam Godzik)
- "Joint Center for Protein Modeling", P20 GM076221, National Institute of General Medical Sciences, National Institute of Health (Co-PI; PI: Adam Godzik)